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Caption: Adult human fibroblast cells (left) are reprogramed into human induced pluripotent stem cells(iPS cells). The iPS cells have a characteristic stickiness that lets them to adhere to sorting devices(right) with different strengths than other cells.Credit: Ankur Singh and Andres Garcia, Institute for Bioengineering & Bioscience, Georgia Tech There is much excitement about the Continue reading Exploiting Stem Cell Stickiness for Sorting … Caption: Anopheles female blood feeding and Plasmodium falciparum eggs in Anopheles mosquito midguts.Credit: Image courtesy of Jose Luis Ramirez, Laboratory of Malaria and Vector Research, NIAID, NIH It turns out that one of the most innovative and effective strategies to fight malaria might involve harnessing a bacterium called Wolbachia. This naturally occurring genus of Continue reading Fighting Malaria, With a Little Help from Bacteria …
Caption: Researcher Zhaoxia Sun, at Yale, uses the zebrafish to study Polycystic Kidney Disease, which affects more than 600,000 Americans. Mutations in the zebrafish vhnf1 gene, and its human counterpart, cause cysts in both zebrafish and human kidneys (as shown by the large “bubble” seen in the mutant fish). [3]Credit: Zhoaxia Sun, Biological & Continue reading Fishing for Answers in Human Disease … Caption: Betatrophin, a natural hormone produced in liver and fat cells, triggers the insulin-producing beta cells in the pancreas to replicateCredit: Douglas Melton and Peng Yi Type 2 diabetes (T2D) has arguably reached epidemic levels in this country; between 22 and 24 million people suffer from the disease. But now there’s an exciting new Continue reading More Beta Cells, More Insulin, Less Diabetes … Caption: Artist rendition of spiny headed worm │The adhesive patch with microneedles that swellSource: The Karp Lab, Brigham and Women’s Hospital Inspiration can come from some pretty strange sources. Case in point: a new adhesive Band-Aid inspired by Pomphorhynchus laevis, a spiny-headed worm that lives in the intestines of fish. The parasitic worm pokes Continue reading Spiny Worm Inspires Next-Gen Band-Aid … |
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