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Putting Bone Metastasis in the Spotlight

When cancers spread, or metastasize, from one part of the body to another, bone is a frequent and potentially devastating destination. It’s a particularly common and painful problem for people with advanced cancers of the breast and prostate. Now, as you can see in this video, an NIH-funded research team has developed a new system that hopefully will provide us with a better understanding of what goes on when cancer cells invade bone.

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Gene Editing in Dogs Boosts Hope for Kids with Muscular Dystrophy

CRISPR and other gene editing tools hold great promise for curing a wide range of devastating conditions caused by misspellings in DNA. Among the many looking to gene editing with hope are kids with Duchenne muscular dystrophy (DMD), an uncommon and tragically fatal genetic disease in which their muscles—including the heart, extremities, and the main muscle used for breathing—gradually become too weak to function. Such hopes were recently buoyed by a new study that showed infusion of the CRISPR/cas9 gene editing system could halt disease progression in a dog model of DMD.

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