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Creative Minds: Teaming Math and Science for an HIV Cure

Posted on by Dr. Francis Collins

Alison Hill

Alison Hill

You may have heard about young mathematicians who’ve helped to design cooler cars, smarter phones, and even more successful sports teams. But do you know about the young mathematician who is helping to find a cure for the estimated 35 million people worldwide infected with the human immunodeficiency virus (HIV)? If not, I’d like to introduce you to Alison Hill, a mathematical biologist at Harvard University, Cambridge, MA.

Recognized this year by Forbes Magazine’s 30 Under 30 as one of the most important young innovators in healthcare, Hill is teaming with clinicians to develop sophisticated mathematical tools to predict which experimental drugs might work to clear HIV from the body once and for all. While current treatments are able to reduce some patients’ HIV burden to very low or even undetectable levels, it is eradication of this viral reservoir that stands between such people living with a serious, but controllable chronic disease and actually being cured.


Connecting the Dots: The State of U.S. Health, 1990-2010

Posted on by Dr. Francis Collins

Caption: Adapted from Figure 2, The state of US health, 1990-2010: burden of diseases, injuries, and risk factors. US Burden of Disease Collaborators. JAMA. 2013 Aug 14;310(6):591-608. 

Kudos to the U.S. Burden of Disease Collaborators and their recent report on the state of U.S. health from 1990 to 2010. This team, supported by NIH and the Bill and Melinda Gates Foundation, documented how the incidence of various diseases and injuries has changed over the past two decades in terms of toll they take on Americans’ health and well being. That toll is measured in something called disability-adjusted life years (DALYs), which amounts to the sum of years of life lost due to premature death and years lived with disability.