HIV latency-reversing drugs
Creative Minds: Teaming Math and Science for an HIV Cure
Posted on by Dr. Francis Collins
You may have heard about young mathematicians who’ve helped to design cooler cars, smarter phones, and even more successful sports teams. But do you know about the young mathematician who is helping to find a cure for the estimated 35 million people worldwide infected with the human immunodeficiency virus (HIV)? If not, I’d like to introduce you to Alison Hill, a mathematical biologist at Harvard University, Cambridge, MA.
Recognized this year by Forbes Magazine’s 30 Under 30 as one of the most important young innovators in healthcare, Hill is teaming with clinicians to develop sophisticated mathematical tools to predict which experimental drugs might work to clear HIV from the body once and for all. While current treatments are able to reduce some patients’ HIV burden to very low or even undetectable levels, it is eradication of this viral reservoir that stands between such people living with a serious, but controllable chronic disease and actually being cured.
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Tags: AIDS, antiretroviral drugs, combination therapy, HIV, HIV cure, HIV latency-reversing drugs, human immunodeficiency virus, immunology, latent infection, mathematical biology, mathematics, NIH Early Independence Award, virology