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X-linked retinoschisis

Glowing Proof of Gene Therapy Delivered to the Eye

Posted on by Dr. Francis Collins

Cross section of a retina stained red, green, and blue

Caption: A cross section from the retina of a non-human primate shows evidence of the production of a glowing green protein, made from genes the virus delivered —proof that the genetic cargo entered all layers of the outer retina. Cell nuclei are labeled in blue and the laminin protein is labeled in red.
Credit: Leah Byrne, University of California, Berkeley

Scientists based at Berkeley have engineered a virus that can carry healthy genes through the jelly-like substance in the eye to reach the cells that make up the retina—the back of the eye that detects light.