tumor microenvironment of metastasis
Posted on by Dr. Francis Collins
If you’re a fan of the Mission: Impossible spy thrillers, you might think that secret agent Ethan Hunt has done it all. But here’s a potentially life-saving mission that his force has yet to undertake: spying on cancer cells. Never fear—some scientific sleuths already have!
So, have a look at this bio-action flick recently featured in the American Society for Cell Biology’s 2015 Celldance video series. Without giving too much of the plot away, let me just say that it involves cancer cells escaping from a breast tumor and spreading, or metastasizing, to other parts of the body. Along the way, those dastardly cancer cells take advantage of collagen fibers to make a tight-rope getaway and recruit key immune cells, called macrophages, to serve as double agents to aid and abet their diabolical spread.
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Tags: blood vessel, breast cancer, cancer, cancer cells, cancer imaging, cancer metastasis, CellDance 2015, collagen, imaging, intravital microscopy, IVM, macrophage, metastasis, oncology, primary tumor, TMEM, tumor metastasis, tumor microenvironment, tumor microenvironment of metastasis