Credit: David Goodsell, The Scripps Research Institute
This lively interplay of shape and color is an artistic rendering of the Zika virus preparing to enter a cell (blue) by binding to its protein receptors (green). The spherical structures (pink) represent two Zika viruses in a blood vessel filled with blood plasma cells (tan). The virus in the middle in cross section shows viral envelope proteins (red) studding the outer surface, with membrane proteins (pink) embedded in a fatty layer of lipids (light purples). In the innermost circle, you can see the viral genome (yellow) coiled around capsid proteins (orange).
This image was sketched and hand-painted with watercolors by David Goodsell, a researcher and illustrator at The Scripps Research Institute, La Jolla, CA. Goodsell put paint and science to paper as part of the “Molecule of the Month” series run by RCSB Protein Data Bank (PDB), which NIH co-supports with the National Science Foundation and the Department of Energy. The PDB, which contains structural data on thousands of proteins and small molecules, uses its “Molecule of the Month” series to help students visualize a molecule or virus and to encourage their exploration of structural biology and its applications to medicine.
Thanks to your swift and overwhelming response, the NIH Director’s Blog survey is now closed. I’d like to thank everyone who took the time to respond. Your feedback is greatly appreciated and will be used to help shape the blog as we move forward.
From my “house” at NIH to yours, I’d like to wish each of you and your loved ones a wonderful holiday season and a happy, healthful New Year. Throughout the past year, I hope that you’ve enjoyed the entries in this blog, sharing just a few of the many breakthroughs in biomedical research and introducing you to some of the young scientists who fill me with such hope for the future. As we prepare to turn the NIH Director’s Blog calendar to 2016, I look forward to bringing you even more exciting discoveries that show the power of science to build a healthier tomorrow.
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