Creative Minds: Potential Diabetes Lessons from Binge-Eating Snakes
Posted on by Dr. Francis Collins
Many people would do just about anything to avoid an encounter with a snake. Not Stephen Secor. Growing up in central New York State, Secor was drawn to them. He’d spend hours frolicking through forest and field, flipping rocks and hoping to find one. His animal-loving mother encouraged him to keep looking, and she even let him keep a terrarium full of garter snakes in his bedroom. Their agreement: He must take good care of them—and please make sure they don’t get loose.
As a teen, Secor considered a career as a large-animal veterinarian. But a college zoology course led him right back to his fascination with snakes. Now a professor at the University of Alabama, Tuscaloosa, he’s spent 25 years trying to understand how some snakes, such as the Burmese python shown above, can fast for weeks or even months, and then go on a sudden food binge. Secor’s interest in the feast-or-famine digestive abilities of these snakes has now taken an unexpected turn that he never saw coming: a potential treatment to help people with diabetes.
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Tags: anti-diabetes drugs, beta cells, Burmese pythons, diabetes, diet, digestion, fatty acids, insulin, metabolism, NIH Director’s 2016 Transformative Research Award, pancreas, pancreatic beta cells, reptiles, small molecules, snakes, tissue regeneration