While earning her Ph.D. in clinical psychology, Dylan Gee often encountered children and adolescents battling phobias, panic attacks, and other anxiety disorders. Most overcame them with the help of psychotherapy. But not all of the kids did, and Gee spent many an hour brainstorming about how to help her tougher cases, often to find that nothing worked.
What Gee noticed was that so many of the interventions she pondered were based on studies in adults. Little was actually known about the dramatic changes that a child’s developing brain undergoes and their implications for coping under stress. Gee, an assistant professor at Yale University, New Haven, CT, decided to dedicate her research career to bridging the gap between basic neuroscience and clinical interventions to treat children and adolescents with persistent anxiety and stress-related disorders.
Tags: 2015 NIH Director’s Early Independence Award, adolescents, amygdala, anxiety, anxiety disorders, behavior, brain, brain development, brain imaging, child health, children, clinical psychology, cognition, conditioning, fear, hippocampus, memory, mental health, MRI, neuroscience, phobia, prefrontal cortex, psychiatry, psychotherapy, safety signals, sensory cues, stress
Most neuroscientists make their discoveries in a traditional laboratory or clinical setting. Sean Escola, a theoretical neuroscientist at Columbia University in New York, just needs a powerful computer and, judging from his photo, a good whiteboard.
Using data that he and his colleagues have recorded from living brain cells, called neurons, Escola crunches numbers to develop rigorous statistical models that simulate the activity of neuronal circuits within the brain. He hopes his models will help to build a new neuroscience that brings into sharper focus how the brain’s biocircuitry lights up to generate sensations and thoughts—and how it misfires in various neurological disorders, particularly in mental illnesses.
Tags: brain, BRAIN Initiative, brain research, brain states, computational neuroscience, mental illnesses, neural computation, neuronal circuits, neuroscience, neuroscientist, obsessive-compulsive disorders, psychiatry, theoretical neuroscience, transitionopathies