oxidative stress
Possible Explanation for Why Some People Get More Colds
Posted on by Dr. Francis Collins
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Colds are just an occasional nuisance for many folks, but some individuals seem to come down with them much more frequently. Now, NIH-funded researchers have uncovered some new clues as to why.
In their study, the researchers found that the cells that line our airways are quite adept at defending against cold-causing rhinoviruses. But there’s a tradeoff. When these cells are busy defending against tissue damage due to cigarette smoke, pollen, pollutants, and/or other airborne irritants, their ability to fend off such viruses is significantly reduced [1].
The new findings may open the door to better strategies for preventing the common cold, as well as other types of respiratory tract infections caused by non-flu viruses. Even small improvements in prevention could have big implications for our nation’s health and economy. Every year, Americans come down with more than 500 million colds and similar infections, leading to reduced work productivity, medical expenses, and other costs approaching $40 billion [2].
LabTV: Young Scientist on a Mission to Cure Alzheimer’s Disease
Posted on by Dr. Francis Collins
Time for another LabTV video! Today, I’d like you to meet Melissa Young, a third-year graduate student in the College of Pharmacy, University of Georgia, Athens. Young, who is doing research in the lab of James Franklin, says her scientific goal is to help build the scientific case that oxidative stress plays a key role in Alzheimer’s disease.
Young also has a personal reason for wanting to her research to succeed. From her experiences with a beloved grandmother and aunt, she has seen first-hand the heartbreaking effects of Alzheimer’s disease and other forms of dementia on both patients and their loved ones. Currently, there is no cure for Alzheimer’s disease and no treatments to halt or reverse its progression. That’s one of the reasons why Young has chosen to go into an area of science focused on translating basic discoveries into new therapeutics.
