Vaccines are one of biomedicine’s most powerful and successful tools for protecting against infectious diseases. While we currently have safe and effective vaccines to prevent measles, mumps, and a great many other common childhood diseases, we still lack a vaccine to guard against respiratory syncytial virus (RSV)—a leading cause of pneumonia among infants and young children.
Each year, more than 2 million U.S. children under the age of 5 require medical care for pneumonia and other potentially life-threatening lower respiratory infections caused by RSV [1,2]. Worldwide, the situation is even worse, with more than 30 million infections estimated to occur annually, most among kids in developing countries, where as many as 200,000 deaths may result . So, I’m pleased to report some significant progress in biomedical research’s long battle against RSV: encouraging early results from a clinical trial of an experimental vaccine specifically designed to outwit the virus.
Tags: childhood disease, childhood infectious diseases, childhood vaccine, clinical trial, CRADA, genetic engineering, global health, immunity, live vaccine, M2-2 gene, neutralizing antibodies, pneumonia, respiratory diseases, respiratory syncytial virus, RSV, RSV MEDI ΔM2-2, RSV vaccine, translational medicine, vaccine, virology