Posted on by Dr. Francis Collins
Whether you’re 6 or 60, your path through life has probably been guided in more ways than you completely realize by a short list of individuals who inspired you. Maybe they opened your eyes to an unforeseen opportunity. Maybe they challenged you to reach higher than you thought you could, and helped you believe in yourself. Maybe they guided you over a rough spot when all your dreams seemed to be coming apart. Maybe they modeled the kind of honesty, integrity, and generosity that drew you to them—and made you want to follow their example.
We call those people mentors. And the gifts they give us are priceless.
I have been fortunate to have been guided by a number of wonderful mentors. First and foremost were my parents—free spirits who taught me to love learning and seek out new experiences. Then there was a chemistry teacher in 10th grade who inspired me to pursue a career in science. And there were many others in college, graduate school, medical school, and beyond.
But today, I want to recognize Henry Neil Kirkman, M.D., a dedicated pediatrician in North Carolina who introduced me to the amazing field of human medical genetics and started me down a lifelong path of discovery.
I met Dr. Kirkman in December 1973. I was a first year medical student at UNC Chapel Hill, and he had come to my class to teach just three lectures in genetics. I had migrated into medicine from physical chemistry, but I was still searching for something that would unite my affection for mathematics with my awe and appreciation for the intricacies of the human body. Dr. Kirkman’s approach to teaching was perfect—he taught us the principles of inheritance, and he insisted that we not memorize anything (which was in stark contrast to the rest of the medical school curriculum!). Most important, however, was that he brought patients to class. As he presented a child with Down syndrome and a young man with sickle cell disease, I could see the connection between those abstract concepts of inheritance and their human consequences. And I was utterly transformed. I knew I wanted this to be my lifelong focus in medicine.
As a medical student I only met with Dr. Kirkman occasionally, but his influence was profound. He was always soft-spoken, modest, and self-effacing—but his dedication to patients, research, and teaching spoke volumes. He showed me how merging genetics and medicine could become a vision for the future. That vision became an abiding passion for me, giving rise to the development of gene hunting techniques that ultimately led to the discovery of the cystic fibrosis gene—and other puzzles in human genetics that continue to intrigue me to this day, as my lab conducts research on diabetes and aging.
I was saddened to hear of Dr. Kirkman’s passing a few days ago. I will miss him, and I will always be grateful that I had a chance to tell him what a profound impact he had on me.
Do you have mentors that have given you gifts of inspiration and encouragement? I hope so. And if you do, and if you have never told them how much that meant, this would be a great day to write a note.