Christine Ann Denny
Creative Minds: Lighting Up Memory
Posted on by Dr. Francis Collins
One of the most debilitating, and heartbreaking, consequences of Alzheimer’s disease is the way it slowly robs people of their memories. Unfortunately, we don’t yet have a cure for Alzheimer’s, let alone a good understanding of exactly how this disease destroys memory skills. That’s why, in this first post in my series highlighting some of the awardees in NIH Common Fund’s High-Risk, High-Reward Research Program, I’m excited to introduce a young scientist who’s using some cool technology to tackle this formidable challenge: Christine Ann Denny.
A winner of a 2013 NIH Director’s Early Independence Awards (often called the “skip-the-postdoc” award), Denny has developed a technique to label the cells that encode individual memories in the brains of mice. That’s right: she tags the nerve cells that build these memories, the neurons, with a fluorescent molecule that glows.