Advances since HGP

Posted on April 19th, 2013 by

Quantitative Advances Since the Human Genome Project (HGP)
HGP Begins (1990), HGP Ends (2003), 10 Years after HGP (2013)
Genome Sequencing
Cost to Generate a Human Genome Sequence ~$1 billion, ~$10-50 million, ~$3-5 thousand
Time to Generate a Human Genome Sequence ~6-8 years, ~3-4 months, ~1-2 days
Human Genome Sequences 0, 1, Thousands
Genome Sequence Data
Total DNA Bases in GenBank ~49 million, ~31 terabases, ~150 terabases
Whole-Genome Shotgun Bases in GenBank 0, ~9.6 terabases, ~391 terabases
Vertebrate Genome Sequences 0, 3, 112
Non-Vertebrate, Eukaryotic Genome Sequence 0, 14, 455
Prokaryotic Genome Sequences 0, 167, 8760
Human Single-Nucleotide Polymorphisms ~4.4 thousand, ~3.4 million, ~53.6 million
Human Genetics
No. Genes with Known Phenotype/ Disease-Causing Mutation 53 ,1474, 2972
No. Phenotypes/Disorders with Known Molecular Basis 61, 2264, 4847
No. Published Genome-Wide Association Studies (GWAS) 0, 0, 1542
Replicated Disease-Associated Genetic Variants 0, 6, ~2900
Genomic Medicine
Drugs with Pharmacogenomics Information on Label 4, 46, 106

Since the beginning of the Human Genome Project 23 years ago, genomic data have steadily accumulated, laying the foundation for advances in human health.
Data compiled from various sources by National Human Genome Research Institute.