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Editor: Bijal Trivedi

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Brown Fat, White Fat, Good Fat, Bad Fat

Caption: Brown fat cells (stained brown with antibodies against the brown fat-specific protein Ucp1) nestled in amongst white fat cells.Credit: Patrick Seale, University of Pennsylvania School of Medicine

Fat has been villainized; but all fat was not created equal. Our two main types of fat—brown and white—play different roles. Now, two teams of NIH-funded

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Protein Machines at Work

This video shows a molecular view of the reactions that take place inside the pyruvate dehydrogenase complex, a protein machine found in the cell’s powerhouse, the mitochondria. 3D imaging of this machine by high-resolution electron microscopy reveals how the different components essential for the reaction are organized. Watch the flexible arms move inside the

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Science Becomes Art

Credit: Dylan T. Burnette, NICHD, NIH

This stunning picture of a human bone cancer cell won artistic accolades: 3rd place in the Nikon Small World Competition. DNA, the blueprint of life, is actually blue in this photo. The yellow squiggles are little powerhouses called mitochondria that generate ATP ‘fuel’ for the cell. The purple

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