Cool Videos: Accelerating Discoveries Toward Better Health

Clinical and Translational Science video screenshot

One of the biggest challenges in biomedical research today is breaking down the barriers that slow the translation of new scientific discoveries into treatments and cures. Today’s video drives home that point through a parody of the Emmy Award-winning TV series, “Breaking Bad.”

Shot in Albuquerque by the University of New Mexico’s Clinical and Translational Science Center, this film focuses on a dramatic but obviously fictional example of what it takes to move fundamental knowledge about biology into a therapy that can make a difference in a patient’s life. Here’s the plot in a nutshell: “Walter White explains to his class that clinical and translational science is about accelerating basic science to clinical science and then into practice, bringing new discoveries and technology to the people. This parody shows how Walter and Jesse Pinkman bring basic science to clinical practice, and enable a multiple sclerosis (MS) patient to walk again.”

Links:

Clinical & Translational Science Center, University of New Mexico Health Sciences Center

Clinical and Translational Science Awards (National Center for Advancing Translational Sciences/NIH)

NIH Common Fund Video Competition

NIH support: Common Fund; National Center for Advancing Translational Sciences

Cool Videos: Diving for Drugs

Therapies From the Sea video sceenshot

Who says biomedical scientists always have to work indoors? The next installment in our mini-film fest proves otherwise, offering a close-up look at some medicinal chemists who are busy carrying out their research in warm waters off the Florida Keys.

This aquatic adventure may not be as action-packed as “Pirates of the Caribbean” or “Finding Nemo.” But these researchers from the University of Florida College of Pharmacy in Gainesville are out to discover something far more valuable to patients than sunken treasure: marine life with chemical compounds that may provide the basis for new treatments and cures.

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Cool Videos: Myotonic Dystrophy

Myotonic Dystrophy Video screenshot

Today, I’d like to share a video that tells the inspirational story of two young Massachusetts Institute of Technology (MIT) researchers who are taking aim at a genetic disease that has touched both of their lives. Called myotonic dystrophy (DM), the disease is the most common form of muscular dystrophy in adults and causes a wide variety of health problems—including muscle wasting and weakness, irregular heartbeats, and profound fatigue.

If you’d like a few more details before or after watching these scientists’ video, here’s their description of their work:  “Eric Wang started his lab at MIT in 2013 through receiving an NIH Early Independence Award. Learn about the path that led him to study myotonic dystrophy, a disease that affects his family. Eric’s team of researchers includes Ona McConnell, an avid field hockey goalie who is affected by myotonic dystrophy herself. Determined to make a difference, Eric and Ona hope to inspire others in their efforts to better understand and treat this disease.”

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Cool Videos: Metabolomics

Metabolomics video screenshot

Today’s feature in my Cool Video series is a scientific film noir from the University of Florida in Gainesville. Channeling Humphrey Bogart’s hard-boiled approach to detective work, the protagonist of this video is tracking down metabolites—molecules involved in biological mysteries with more twists and turns than “The Maltese Falcon.”

If you’d like a few more details before or after watching the video, here’s how the scientists themselves describe their project: “Inside our cells, chemical heroes, victims, and villains leave behind clues about our health. Meet Dr. Art Edison, one of many metabolomics PIs who are on the case. Their quest? To tail and fingerprint small molecules, called metabolites, which result from the chemical processes that fuel and sustain life. Metabolites can shed light on the state of health, nutrition, or disease in a living thing—whether human, animal, or plant. Funded by National Institutes of Health grant U24DK097209, the University of Florida Southeast Center for Integrated Metabolomics is sleuthing through these cellular secrets.”

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Cool Videos: Alzheimer’s Disease

NIH logo, surrounded by a filmstrip border

To keep everyone energized during the hot, hazy days of summer, I’ve decided to start a new series called Cool Videos. This virtual mini-film fest will feature a variety of videos—some even produced by researchers themselves—in which biomedical science plays a starring role.

Throughout August, you’ll have a chance to screen some of the winners of a recent video competition celebrating the Tenth Anniversary of the NIH Common Fund. These short clips, created by NIH-funded researchers, include a parody of “Breaking Bad,” some underwater camerawork reminiscent of Jacques Cousteau, and even a rap video.

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